Shanghai Johnson & Johnson Pharmaceuticals
This project doubled the size of McNeil Consumer Products’ manufacturing presence in mainland China for the production of Tylenol. The addition is comprised of a one-story addition for the manufacturing and packaging of solid oral dose forms of Tylenol. The mechanical space above the manufacturing rooms incorporates a catwalk system to facility access to ductwork, piping and equipment.
| Square Footage: | 40,000 SF | |
| Construction Budget: | $12,000,000 | |
| Location: | Shanghai, China |
Shanghai Johnson & Johnson Pharmaceuticals
Construction Budget: $12,000,000
Location: Shanghai, China
Shanghai Johnson & Johnson Pharmaceuticals is a joint venture between Johnson & Johnson and Shanghai Pharmaceuticals, a Chinese national pharmaceutical company. Together they manufacture Tylenol for the Chinese and far-east markets.
Jacobs/Wyper was chosen to design, document and provide construction administration services for this overseas project. The design team’s location in the Philadelphia area provided ready access to both Johnson & Johnson’s global engineering group in New Brunswick, New Jersey and McNeil Pharmaceutical’s Tylenol production experts in Fort Washington, Pennsylvania. Johnson & Johnson saw this as a way to manage design quality and facilitate technology transfer.
The existing 40,000 SF structure is 3 stories tall. It had numerous cGMP compliance issues arising out of conflicts and crossings in the flow of material and personnel. The new addition both increases the production capacity while addressing these compliance issues.
In the new design the existing structure is maintained predominately for non-GMP functions such as shipping/receiving and warehousing. The new addition locates an employee entrance and locker room immediately adjacent to the existing building serving as a separation and link between the old and the new construction. The new production floor is located on the opposite side of the entrance/locker room. This configuration allows personnel to exit the locker rooms directly into GMP or non-GMP areas. The production area is designed to utilize totes for the processing and transportation of material between processes. Processes include granulation, blending, compression and coating. Two primary and secondary packaging lines complete the production flow.
A pre-manufactured metal building was selected as the building structure and enclosure. This allowed for both speed of construction and a reliable level of quality. The interior was fit out primarily with plaster on CMU walls and included terrazzo floors throughout. The judicious selection of local and offshore materials and contractors resulted in a successful project.
