University of Pennsylvania Cyclotron Expansion

The Cyclotron Lab is a small drug manufacturing facility situated beneath a public park at the School of Medicine. The site is highly constrained, situated between two multistory buildings on a city street – a brick-clad entrance pavilion sits above, while the lab space below is enclosed within radiation-shielding concrete vaults. The cyclotron itself produces a biologically-active molecule with a positron-emitting radionuclide for use as tracer drugs in PET Scanners or PET CT Scanners. The expansion houses a second 18MeV cyclotron, with an external target station, and four class 10,000 GMP labs that house hot cells for the production of radiopharmacology products.


Philadelphia, Pennsylvania


3,000 sf

Project Principal

Jamie Wyper

Project Manager

Eric H. Bohn